Recombinant Human papillomavirus type 18 Protein E6 from MyBioSource.com

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Recombinant Human papillomavirus type 18 Protein E6

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Description

Transcriptional transactivator. Binds double-stranded DNA. Has transforming activity. Inactivates, with E6-AP ubiquitin-protein ligase, the human p53/TP53 tumor suppressor protein by targeting it to degradation. Binds and targets human MUPP1/MPDZ protein to degradation. Those two functions presumably contribute to transforming activity. Interaction with human FBLN1 protein also ses to be linked to cell transformation