Z-YVAD-FMK (Ready-to-Use) from Enzo Life Sciences, Inc.

Product Specs
ItemZ-YVAD-FMK (Ready-to-Use)
CompanyEnzo Life Sciences, Inc.
Price $189.00Supplier Page View Company Product Page
Catalog NumberALX-260-154-R100
Quantity100 µl
FormatLiquid. In DMSO
Purity≥99% (HPLC)
Molecular Weight630.7
Molecule NameZ-YVAD-FMK (Ready-to-Use)
Source/Expression SystemSynthetic
TypePeptide

Specifications/Features

Inhibitor of caspase-1 and -4

Sequence

Z-Tyr-Val-Ala-Asp(OMe)-fluoromethylketone

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Enzo Life Sciences, Inc.

10 Executive Blvd.

Farmingdale, NY 11735

United States

Phone: 800-942-0430
Fax: 610-941-9252

Company Profile

Website: www.enzo.com

(1) TH17 cells promote CNS inflammation by sensing danger signals via MincleNature communicationsMay 3, 2022Zhang Q, Liu W, Wang H, Zhou H, Bulek K, Chen X, Zhang CJ, Zhao J, Zhang R, Liu C, et al.Electron Microscopy Sciences. Caspase-Glo 8 assay system (Kit#G8200) was purchased from Promega. YVAD-fmk (ALX-260-154-R100) and IETD-fmk (550380) were purchased from Enzo and BD. Synthetic β-GluCer [d18:1/C24:1(15Z), C18:0,

(2) Nickel induces inflammatory activation via NF-κB, MAPKs, IRF3 and NLRP3 inflammasome signaling pathways in macrophagesAgingDecember 10, 2019Guo H, Liu H, Jian Z, Cui H, Fang J, Zuo Z, Deng J, Li Y, Wang X, Zhao L, et al.Santa Cruz Biotechnology. Tetramethylrhodamine, methyl ester (TMRM) was obtained from AnaSpec Inc. (#CA94555). Z-YVAD-FMK (ALX-260-154-R100) was purchased from Enzo Life Sciences. MitoSOX (M36008) was obtained from Invitrogen. The antibodies

(3) Platelet-activating factor (PAF) mediates NLRP3-NEK7 inflammasome induction independently of PAFRThe Journal of experimental medicineDecember 2, 2019Deng M, Guo H, Tam JW, Johnson BM, Brickey WJ, New JS, Lenox A, Shi H, Golenbock DT, Koller BH, et al.VAS2870 (#19205), Ro 20-1724 (#18272), and forskolin (#11018) from Cayman Chemical; and zYVAD-fmk (#ALX-260-154-R100), zVAD-FMK (#ALX-260-138-R100), Mitotempo (#ALX-430-150-M005), DPI (#ALX-270-003), Ca-074-Me (#BML-PI126-0001),

(4) Inflammasome-Driven Interleukin-1α and Interleukin-1β Production in Atherosclerotic Plaques Relates to Hyperlipidemia and Plaque ComplexityJACC. Basic to translational scienceJune 1, 2019Jiang X, Wang F, Wang Y, Gisterå A, Roy J, Paulsson-Berne G, Hedin U, Lerman A, Hansson GK, Herrmann J, et al.experiments, MCC950 (PZ0280, Sigma-Aldrich) or the caspase inhibitor Z-Val-Ala-Asp fluoromethyl ketone (ALX-260-154-R100, Enzo Life Sciences) was applied at indicated concentrations 2 h prior to adding LPS or ATP. Thereafter,

(5) TLR-stimulated IRAKM activates caspase-8 inflammasome in microglia and promotes neuroinflammationThe Journal of clinical investigationDecember 3, 2018Zhang CJ, Jiang M, Zhou H, Liu W, Wang C, Kang Z, Han B, Zhang Q, Chen X, Xiao J, et al.ab181949) were from Abcam. Caspase-1/8 FLICA (97 and 99) were purchased from ImmunoChemistry. YVADfmk (ALX-260-154-R100) and IETD-fmk (550380) were purchased jci.org Volume 128 Number 12 December 2018 5409 RESEARCH

(6) T cell-intrinsic ASC critically promotes T(H)17-mediated experimental autoimmune encephalomyelitisNature immunologyMay 1, 2016Martin BN, Wang C, Zhang CJ, Kang Z, Gulen MF, Zepp JA, Zhao J, Bian G, Do JS, Min B, et al.Electron Microscopy Sciences. Caspase-8 Flica (Kit#99) was purchased from ImmunoChemistry. YVAD-fmk (ALX-260-154-R100) and IETD-fmk (550380) were purchased from Enzo and BD. Anti-IL-1β-PE antibody (1:300, IC4013P) was

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Z-YVAD-FMK (Ready-to-Use) from Enzo Life Sciences, Inc.

Description

Specifications/Features

Sequence

Enzo Life Sciences, Inc.

Citations (6)

Reviews

Z-YVAD-FMK (Ready-to-Use) from Enzo Life Sciences, Inc.

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