Description
VOPP1 has beenpreviously shown to be over-expressed in human glioblastoma multiforme andsquamous cell carcinoma. VOPP1 is a key regulator of NF-kappa-B signaling,and that high-level, amplification-mediated VOPP1 expression, such as thatoccurring in tumors with amplified EGFR, could contribute to resistance toapoptosis