Description
CHMP1B, also knownas charged multivesicular body protein 1b, is probable peripherallyassociated component of the endosomal sorting required for transport complexIII (ESCRT-III) which is involved in multivesicular bodies (MVBs) formationand sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminalvesicles (ILVs) that are generated by invagination and scission from thelimiting membrane of the endosome and mostly are delivered to lysosomesenabling degradation of membrane proteins, such as stimulated growth factorreceptors, lysosomal enzymes and lipids