Description
ERCC1, also known asDNA excision repair protein ERCC-1, functions in the nucleotide excisionrepair pathway, and is required for the repair of DNA lesions such as thoseinduced by UV light or formed by electrophilic compounds including cisplatin.Defects in ERCC1 are the cause of cerebro-oculo-facio-skeletal syndrome type4 (COFS4)