Description
The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2.These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1.As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation.In some cases, expression of the FOS gene has also been associated with apoptotic cell death