Description
RNMT is a widelyexpressed nuclear protein that belongs to the mRNA cap methyltransferasefamily. Cap-dependent mRNA translation requires the methylation of the mRNAguanosine cap by RNMT. RNMT catalyzes the transfer of a methyl group fromAdoMet (S-adenosylmethionine) to the GpppN end of the growing mRNA at the N-7position, thereby producing AdoHyc (S-adenosylhomocysteine) and m7GpppNterminated RNA