Description
Met is aglycosylated receptor tyrosine kinase that plays a central role in epithelialmorphogenesis and cancer development. Met is synthesized as a single chainprecursor which undergoes cotranslational proteolytic cleavage. This generatesa mature Met that is a disulfide-linked dimer composed of a 50 kDaextracellular α chain and a 145 kDa transmembrane β chain