NEDD8 Protein UL-812-500 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemNEDD8 Protein
CompanyR&D Systems, a Bio-Techne Brand
Price $271.00Supplier Page View Company Product Page
Catalog NumberUL-812-500
Size500 ug
ApplicationsEnzyme Activity
Conjugate/TagUnconjugated
FormatSupplied as a solution in HEPES, NaCl and DTT
Purity>95%, by SDS-PAGE under reducing conditions and visualized by Colloidal Coomassie® Blue stain
SpeciesHuman, Mouse, Rat
Molecule NameNEDD8
Source/Expression SystemE. coli-derived Recombinant Human/Mouse/Rat NEDD8 Protein, CF
NCBI Full Gene NameNEDD8 ubiquitin like modifier
NCBI Gene AliasesNEDD-8
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 6 months from date of receipt, -70 °C as supplied. 3 months, -70 °C under sterile conditions after opening

Specifications/Features

Available conjugates: Sizes Available: 500 ug

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) COP9 signalosome and PRMT5 methylosome complexes are essential regulators of Lis1-dynein-based transportCell reportsJanuary 27, 2026Gupta D, Maddika S.

(2) Chemically-induced degradation of the endoplasmic-reticulum stress sensor IRE1 by a VHL-recruiting chimeraNat CommunDecember 11, 2025Jin Du, Elisia Villemure, Matthew Johnson, Caleigh Azumaya, Catarina J. Gaspar, Scot Marsters, David Lawrence, Scott Foster, Alexis Rohou, Tommy K. Cheung, et al.(E2-616-100), UBE2D2 (E2-622-100), ubiquitin (U-100H-10M), methylated ubiquitin (U-502-01M), and NEDD8 (UL-812-500) were purchased from Biotechne. Detection of polyubiquitin linkage and site of ubiquitination by mass-spectrometry For

(3) A LisH-domain protein interaction map reveals a Lis1-ARIH2-dynein regulatory axisiScienceNovember 21, 2025Devanshi Gupta, Subbareddy Maddikaprotein,R&D systems,Cat#E-313-025 Nedd8 UBE2M,R&D systems,Cat#E2-656-100 Nedd8 purified,R&D systems,Cat#UL-812-500 ,, Deposited data,Deposited data,Deposited data ,, Human LisH domain containing protein interaction

(4) The unique structure of the highly conserved PPLP region in HIV-1 Vif is critical for the formation of APOBEC3 recognition interfacesmBioMarch 12, 2025Iwatani Y, Matsuoka K, Ode H, Kubota M, Nakata Y, Setoyama Y, Kojima K, Imahashi M, Yokomaku Y.

(5) Monoubiquitination empowers ubiquitin chain elongationThe Journal of biological chemistryMarch 1, 2024Wu K, DeVita RJ, Pan ZQ.

(6) Determining the Effects of Neddylation on Cullin-RING Ligase-Dependent Protein UbiquitinationCurr ProtocMarch 1, 2022Wang K, Liu X.10×),1× DTT (see recipe for 1 M),2 mM ATP (see recipe for 200 mM),2 mM "NEDD8 (R&D Systems, cat. no. UL‐812‐500)",2 μM "NAE (R&D Systems, cat. no. E‐313‐025)",0.25 μM "UBC12 (R&D Systems, cat. no. E2‐656‐100)",3

(7) Structural insights into Cullin4-RING ubiquitin ligase remodelling by Vpr from simian immunodeficiency virusesPLoS pathogensAugust 1, 2021Banchenko S, Krupp F, Gotthold C, Bürger J, Graziadei A, O'Reilly FJ, Sinn L, Ruda O, Rappsilber J, Spahn CMT, et al.

(8) Targeting a helix-in-groove interaction between E1 and E2 blocks ubiquitin transferNature chemical biologyNovember 1, 2020Cathcart AM, Bird GH, Wales TE, Herce HD, Harvey EP, Hauseman ZJ, Newman CE, Adhikary U, Prew MS, Oo T, et al.

(9) Cand1-Mediated Adaptive Exchange Mechanism Enables Variation in F-Box Protein ExpressionMolecular cellMarch 1, 2018Liu X, Reitsma JM, Mamrosh JL, Zhang Y, Straube R, Deshaies RJ.

(10) A potent small-molecule inhibitor of the DCN1-UBC12 interaction that selectively blocks cullin 3 neddylationNature communicationsOctober 27, 2017Zhou H, Lu J, Liu L, Bernard D, Yang CY, Fernandez-Salas E, Chinnaswamy K, Layton S, Stuckey J, Yu Q, et al.

(11) The ubiquitin-associated (UBA) domain of SCCRO/DCUN1D1 protein serves as a feedback regulator of biochemical and oncogenic activityThe Journal of biological chemistryJanuary 2, 2015Huang G, Towe CW, Choi L, Yonekawa Y, Bommeljé CC, Bains S, Rechler W, Hao B, Ramanathan Y, Singh B.

(12) SCCRO3 (DCUN1D3) antagonizes the neddylation and oncogenic activity of SCCRO (DCUN1D1)The Journal of biological chemistryDecember 12, 2014Huang G, Stock C, Bommeljé CC, Weeda VB, Shah K, Bains S, Buss E, Shaha M, Rechler W, Ramanathan SY, et al.

(13) Inhibition of a NEDD8 Cascade Restores Restriction of HIV by APOBEC3GPLoS pathogensDecember 1, 2012Stanley DJ, Bartholomeeusen K, Crosby DC, Kim DY, Kwon E, Yen L, Cartozo NC, Li M, Jäger S, Mason-Herr J, et al.

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NEDD8 Protein from R&D Systems, a Bio-Techne Brand

Specifications/Features

R&D Systems, a Bio-Techne Brand

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NEDD8 Protein from R&D Systems, a Bio-Techne Brand

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