Recombinant TGF-beta 1 (OPSD00037) from Aviva Systems Biology

Description

Transforming Growth Factor-beta 1 (TGF-beta 1) is a member of the TGF-beta superfamily. Members of this family are known to exhibit regulatory activity in immunity and proliferation pathways. TGF-beta 1 signals through SMAD proteins via the TGF-beta1 RI and RII receptors. Mature human TGF-beta1 is a glycosylated homodimer, containing two 112 amino acids chains, with a total molecular weight of 25.6 kDa

Product Specs
ItemRecombinant TGF-beta 1 (OPSD00037)
CompanyAviva Systems Biology
Price $108.00Supplier Page View Company Product Page
Catalog NumberOPSD00037
Size1 ug
ActivityRecombinant humanTGF- beta 1 has full biological activity as compared to a standard.The ED₅₀, determined by the dose-dependent inhibition of IL-4-induced proliferation of mouse HT-2 cells, is 0.05 ng/mL. This corresponds to a specific activity of 2 x 10⁷ units/mg
Purity95% as determined by: reducing and non-reducing SDS-PAGE
TypeProtein
Molecule NameTransforming growth factor beta-1
FormatSterile filtered white lyophilized (freeze-dried) powder. Lyophilized from a sterile filtered aqueous solution containing 10 mM Glycine, 50 mM NaCl, 10% Trehalose, and BSA (4:1 protein to BSA Ratio), pH 4.0
Molecular Weight25.6 kD
NCBI Gene AliasesCED, DPD1, IBDIMDE, LAP, TGF-beta1, TGFB, TGFbeta
NCBI Full Gene Nametransforming growth factor beta 1
Source/Expression SystemHEK 293 cells