Description
This product is recombinant Plasmodium falciparum histidine rich protein-2, a member of the histidine rich protein family found in the malaria parasite. Histidine rich protein-2 is secreted by Plasmodium falciparum into the host erythrocyte cytosol and is expressed on the cell membrane or associated with the cytoskeleton of infected erythrocytes. Histidine rich protein-2 is thought to polymerise free haem to form haemozoin. It is also thought to play a role in the polymerisation of ferriprotoporphyrin IX, a by-product of haemoglobin degradation