Description
A cell permeable inhibitor of PRMTs; inhibits both yeast Hmt1p and human PRMT1 (IC50 = 3.0 and 8.8 µM, respectively); also effectively blocks the activity of PRMTs 3, 4, and 6 but not that of lysine methyltransferases; inhibits HIV-1 reverse transcriptase (IC50 = 5.0 µM)