Description
14-3-3 is a general name given to a family of acidic, soluble, ubiquitously expressed 28kDa proteins that are the products of related but separate genes. They are considered isoforms and are named eta (eta), gamma (gamma), delta/zeta (delta / Xi), alpha/beta (alpha / beta), theta/tau (theta / tau), sigma (sigma) or epsilon (epsilon). Interactions are generally mediated by phosphorylation of specific binding sites in the target proteins. 14-3-3 proteins can exist as monomers, homodimers and heterodimers. Our recombinant 14-3-3 gamma comprises a 246 amino acid fragment (2-247) corresponding to the 14-3-3 gamma coding sequence and is expressed in E. coli with an amino-terminal hexahistidine tag. This product is for research use only and is not intended for diagnostic or therapeutic use