Description
MyBioSource is a major supplier of recombinant human C-Reactive Protein (rCRP) in bulk and research quantities for research and In Vitro diagnostic manufacturing for finished products.
Custom preparations, technical support, bulk quantities and aliquoting available.
C-reactive protein (CRP) is produced by hepatocytes as acute phase reactant to respond to inflammation and tissue damage and consists of five identical subunits under physiological conditions to show pentamer structure as member of pentraxin family.
The American Heart Association and the Centers for Disease Control and Prevention published a joint scientific statement in 2003 on the use of inflammatory markers in clinical and public health practice.
By patented technology pentamerized active recombinant C-Reactive Protein molecule is secreted into culture medium during E.coli fermentation with host cells having human CRP gene, allowing r-hCRP to be excreted without cell lysis. The patented technology specifies only active r-hCRP to be manufactured, which is equivalent to native one originated from human tissues. This product is affinity-purified by use of phosphorylcholine conjugated matrices