Description
Fractalkine is a large cytokine protein containing multiple domains and is the only known member of the CX3C chemokine family. Fractalkine is produced as a long protein (with 373-amino acid in humans) with an extended mucin-like stalk and a chemokine domain on top. The mucin-like stalk permits it to bind to the surface of certain cells. Fractalkine elicits its adhesive and migratory functions by interacting with the chemokine receptor CX3CR1. Our recombinant Fractalkine comprises a 76 amino acid fragment (25-100) corresponding to the chemokine domain of the fractalkine protein and is expressed in E. coli with an aminoterminal hexahistidine tag. This product is for research use only and is not intended for diagnostic or therapeutic use