Description
Cystatin C is a member of the Type 2 cystatin superfamily. It is a potent inhibitor of cysteine proteinases, both endogenous (lysosomal cathepsins), and pathogenic. Cystatin C is found in high concentrations in biological fluids and is expressed by all human nucleated cells. Changes in cystatin C have been documented in a number of cardiovascular diseases, including atherosclerosis, amyloid angiopathy and myocardial infarction. Our recombinant Cystatin C comprises a 120 amino acid fragment (27-146) corresponding to the mature Cystatin C protein and is expressed in E. coli with an amino-terminal hexahistidine tag. This product is for research use only and is not intended for diagnostic or therapeutic use