Description
Annexin 7 is a member of the annexin family of calcium-dependent phospholipids binding proteins. It includes a unique, highly hydrophobic N-terminal domain of 167 amino acids and a conserved C-terminal region of 299 amino acids. The latter is composed of alternating hydrophobic and hydrophilic segments. Analysis of this protein suggests that Annexin 7 is a membrane binding protein with diverse properties including voltage-sensitive calcium channel activity, ion selectivity, and membrane fusion.
Recombinant Human Annexin A7 produced in E. coli is a single, nonglycosylated polypeptide chain containing amino acids 1-466 with a molecular weight of 53.6kDa. It includes a T7 tag at the N-terminus