Description
Description: C6ORF108 produced in E Coli is a single, non-glycosylated polypeptide chain containing 194 amino acids (1-174 a.a.) and having a molecular mass of 21.2kDa.C6ORF108 is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Introduction: C6ORF108 is stimulated by c-Myc protein that is a transcription factor that is involved in the regulation of cell proliferation, differentiation, and apoptosis. C6ORF108 functions in rat in cellular proliferation and c-Myc-mediated transformation. C6ORF108 catalyzes the cleavage of the N-glycosidic bond of deoxyribonucleoside 5''-monophosphates to yield deoxyribose 5-phosphate and a purine or pyrimidine base. Deoxyribonucleoside 5''-monophosphates comprising purine bases are favored to those comprising of pyrimidine bases