Description
Description: The E Coli derived 20 kDa recombinant protein contains the West-Nile N-terminal Pre-M Virus immunodominant regions (MVTLSNFQGKVMMTVNATDVTDVITIPTAAGKNLCIVRAMDVGYLCEDTIT YECPVLAAGNDPEDIDCWCTKSSVYVRYGRCTKTRHSRRSRRSLTVQTH GESTLANKKGAWLDSTKATRYLVKTESWILRNPGYALE).
The protein is fused with 6x His tag at C-terminal.
Introduction: West Nile virus (WNV) is a virus of the family Flaviviridae part of the Japanese encephalitis (JE) antigenic complex of viruses. Image reconstructions and cryoelectron microscopy reveal a 45-50 nm virion covered with a relatively smooth protein surface. This structure is similar to virus; both belong to the genus flavivirus within the family Flaviviridae. WNV is a positive-sense, single strand of RNA, it is between 11,000 and 12,000 nucleotides long which encode seven non-structural proteins (NS1, NS2a, NS3, NS4a, NS4b, and NS5) and three structural proteins (capsid (C), membrane (M or preM), and envelope (E)). The RNA strand is held within a nucleocapsid formed from 12 kDa protein blocks; the capsid is contained within a host-derived membrane altered by two viral glycoproteins