Recombinant Human ATP-dependent translocase ABCB1 (ABCB1), partial MBS9019806 from MyBioSource.com

Description

Translocates drugs and phospholipids across the membrane. Catalyzes the flop of phospholipids from the cytoplasmic to the exoplasmic leaflet of the apical membrane. Participates mainly to the flop of phosphatidylcholine, phosphatidylethanolamine, beta-D-glucosylceramides and sphingomyelins. Energy-dependent efflux pump responsible for decreased drug accumulation in multidrug-resistant cells

Product Specs
ItemRecombinant Human ATP-dependent translocase ABCB1 (ABCB1), partial
CompanyMyBioSource.com
Price $270.00Supplier Page View Company Product Page
Catalog NumberMBS9019806
FormatLiquid or Lyophilized powder
If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8
Size0.02 mg (E-Coli)
Molecular Weight141kDa
PurityGreater than 85% as determined by SDS-PAGE
NCBI Full Gene NameATP binding cassette subfamily B member 1
NCBI Gene AliasesPGY1, ABC20, P-GP, GP170, CLCS, CD243, MDR1, p-170
Domain/Region/Terminus350-710aa; Partial
Molecule NameATP-dependent translocase ABCB1 (ABCB1)
TypeRecombinant Protein
Source/Expression SystemE Coli or Yeast or Baculovirus or Mammalian Cell

Sequence

PSIEAFANAR GAAYEIFKII DNKPSIDSYS KSGHKPDNIK GNLEFRNVHF SYPSRKEVKI LKGLNLKVQS GQTVALVGNS GCGKSTTVQL MQRLYDPTEG MVSVDGQDIR TINVRFLREI IGVVSQEPVL FATTIAENIR YGRENVTMDE IEKAVKEANA YDFIMKLPHK FDTLVGERGA QLSGGQKQRI AIARALVRNP KILLLDEATS ALDTESEAVV QVALDKARKG RTTIVIAHRL STVRNADVIA GFDDGVIVEK GNHDELMKEK GIYFKLVTMQ TAGNEVELEN AADESKSEID ALEMSSNDSR SSLIRKRSTR RSVRGSQAQD RKLSTKEALD ESIPPVSFWR IMKLNLTEWP Y

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