Recombinant Mouse Semaphorin-4C (Sema4c), partial MBS9020668 from MyBioSource.com

Description

Cell surface receptor for PLXNB2 that plays an important role in cell-cell signaling. PLXNB2 binding promotes downstream activation of RHOA and phosphorylation of ERBB2 at 'Tyr-1248'. Required for normal brain development, axon guidance and cell migration. Probable signaling receptor which may play a role in myogenic differentiation through activation of the stress-activated MAPK cascade

Product Specs
ItemRecombinant Mouse Semaphorin-4C (Sema4c), partial
CompanyMyBioSource.com
Price $595.00Supplier Page View Company Product Page
Catalog NumberMBS9020668
FormatLiquid or Lyophilized powder
If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8
Size0.02 mg (Mammalian-Cell)
Molecular Weight92,557 Da
PurityGreater than 90% as determined by SDS-PAGE
NCBI Full Gene Namesema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
NCBI Gene AliasesSemai, Semacl1, sema I, M-Sema F, Semaf
Domain/Region/Terminus21-664aa+IEGRMDP; Partial
Molecule NameSemaphorin-4C (Sema4c)
TypeRecombinant Protein
Source/Expression SystemE Coli or Yeast or Baculovirus or Mammalian Cell

Sequence

AEMWWNLVPR KTVSSGELVT VVRRFSQTGI QDFLTLTLTE HSGLLYVGAR EALFAFSVEA LELQGAISWE APAEKKIECT QKGKSNQTEC FNFIRFLQPY NSSHLYVCGT YAFQPKCTYI NMLTFTLDRA EFEDGKGKCP YDPAKGHTGL LVDGELYSAT LNNFLGTEPV ILRYMGTHHS IKTEYLAFWL NEPHFVGSAF VPESVGSFTG DDDKIYFFFS ERAVEYDCYS EQVVARVARV CKGDMGGART LQKKWTTFLK ARLVCSAPDW KVYFNQLKAV HTLRGASWHN TTFFGVFQAR WGDMDLSAVC EYQLEQIQQV FEGPYKEYSE QAQKWARYTD PVPSPRPGSC INNWHRDNGY TSSLELPDNT LNFIKKHPLM EDQVKPRLGR PLLVKKNTNF THVVADRVPG LDGATYTVLF IGTGDGWLLK AVSLGPWIHM VEELQVFDQE PVESLVLSQS KKVLFAGSRS QLVQLSLADC TKYRFCVDCV LARDPYCAWN VNTSRCVATT S

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