Recombinant Human Caspase-3 (CASP3), partial MBS9019853 from MyBioSource.com

Description

Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-:-Gly-217' bond. Cleaves and activates sterol regulatory elent binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the mbrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin. Triggers cell adhesion in sympathetic neurons through RET cleavage

Product Specs
ItemRecombinant Human Caspase-3 (CASP3), partial
CompanyMyBioSource.com
Price $270.00Supplier Page View Company Product Page
Catalog NumberMBS9019853
FormatLiquid or Lyophilized powder
If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8
Size0.02 mg (E-Coli)
Molecular Weight31,608 Da
PurityGreater than 90% as determined by SDS-PAGE
NCBI Full Gene Namecaspase 3
NCBI Gene AliasesCPP32B, CPP32, SCA-1
Domain/Region/Terminus29-277aa; Partial
Molecule NameCaspase-3 (CASP3)
TypeRecombinant Protein
Source/Expression SystemE Coli or Yeast or Baculovirus or Mammalian Cell

Sequence

SGISLDNSYK MDYPEMGLCI IINNKNFHKS TGMTSRSGTD VDAANLRETF RNLKYEVRNK NDLTREEIVE LMRDVSKEDH SKRSSFVCVL LSHGEEGIIF GTNGPVDLKK ITNFFRGDRC RSLTGKPKLF IIQACRGTEL DCGIETDSGV DDDMACHKIP VEADFLYAYS TAPGYYSWRN SKDGSWFIQS LCAMLKQYAD KLEFMHILTR VNRKVATEFE SFSFDATFHA KKQIPCIVSM LTKELYFYH

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