Description
LY3540378 is a a long-acting relaxin analogue [1]. It is composed a human relaxin mimetic peptide fused to a serum albumin-binding VHH domain. It is selective for relaxin family peptide receptor 1 (RXFP1) compared to RXFP2, 3 and 4. VHH-serum albumin binding extends the peptide's circulating half-life