Deoxyribonuclease I LS002139 from Worthington Biochemical Corporation

Product Specs
ItemDeoxyribonuclease I
CompanyWorthington Biochemical Corporation
Price $110.00Supplier Page View Company Product Page
Catalog NumberLS002139
Source/Expression SystemBovine Pancreas
StorageStore at 2-8°C.PROTECT FROM MOISTURE
Activity≥2,000 Kunitz units per mg dry weight
Size100 mg

Add to Compare List

Worthington Biochemical Corporation

Lakewood, New Jersey 8701

United States

Phone: 1.800.445.9603
1.732.942.1660

Email: custservice@worthington-biochem.com

Company Profile

Website: worthington-biochem.com

(1) An improved preservation method for human dorsal root ganglion neurons enables wider access to human molecular pain neuroscienceCell Reports MethodsMay 18, 2026Joseph B. Lesnak, Mandee K. Schaub, Kimberly Gomez, Aida Calderon-Rivera, Santiago Loya-Lopez, Robert Stewart, Sooyeon Jo, Akie Fujita, Tomás Osorno, Hemanth Mydugolam, et al.Bovine Serum Albumin,Biopharm,71–040 Stemxyme I,Worthington Biochemical,LS004106 DNase I,Worthington Biochemical,LS002139 Recombinant human β-NGF,R&D Systems,256-GF "HBSS (no calcium, no magnesium)",Thermo Scientific,14170–112 BrainPhys

(2) Response of B cells specific for polyomavirus-derived oncoprotein is predictive of Merkel cell carcinoma tumor controlCancer Immunol ResMay 4, 2026Haroldo J. Rodriguez Chevez, Allison J. Remington, Matthew D. Gray, Rian Alam, Macy W. Gilmour, Carina Morningstar, Gabriel F. Alencar, Thomas Pulliam, Erin M. McClure, Neha Singh, et al.incubation in 20 mL of digestion medium composed of RPMI plus 0.002 g DNase (Worthington Biochemical #LS002139), 0.008 g collagenase (Worthington Biochemical #NC991993), and 0.002 g hyaluronidase (Worthington Biochemical

(3) Resolving heterogeneity in Lymph Node Stromal Cells using high-dimensional analysis of non-optimized flow cytometry dataFront BioinformApril 14, 2026Mikala E. Heon, Eduardo Rosa-MolinarCollagenase IV (Worthington Biochemical, Cat#LS004186) and 40 μg/mL DNAse 1 (Worthington Biochemical, Cat#LS002138) in αMEM. The tissue was digested at 37 °C while under constant agitation via gentle rotation. After

(4) Astragalus Polysaccharides Induce Immunogenic Cell Death in Melanoma: A Mechanism Mediated by cGAS/STING Activation via Intratumoral Microbiota ModulationCancer MedApril 14, 2026Xi Qiao, Guiqing Ding, Qijin Lu, Yuxin Chen, Xiaohan Wang, Yuanhua Wang, Jinyun Ma, Xiaodong ChengNeutral protease 1 mg/mL (88922N, Worthington Biochemical, China), and Deoxyribonuclease I 0.02 mg/mL (LS002139, Worthington Biochemical, USA). Tumor draining lymph nodes (TDLNs) were placed into a six‐well plate

(5) Transcriptional and spatial profiling of fibroblasts from human lungs highlights CTHRC1+ cells as fibrogenic signaling hubs in fibrosisbioRxivApril 10, 2026N.D. Vanegas-Avendano, H. Chen, J. Wellmerling, J. Rodriguez-Lopez, A. Ghobashi, V. Peters, C. Sen, B. F. Reader, K. Shilo, B. Gomperts, et al.(Worthington Biochemical, LS002292), dispase (StemCell, 7913), and DNase I (Worthington Biochemical, LS002139). After dissociation, 1X cold wash buffer (Dulbecco’s Modified Eagle Medium (DMEM), high glucose, Gibco,

(6) Protocol for the quantification of digestive exophagy in cell cultureSTAR ProtocMarch 20, 2026Lucy Funes, Frederick R. Maxfield, Santiago Solé-Domènechred,Gibco,31053028 DMSO,Sigma-Aldrich,34869 D-(+)-glucose powder,Sigma-Aldrich,G7021 DNAse I,Worthington Biochemical,LS002139 Fetal Bovine Serum,Thermo Fisher Scientific,10437028 "Fluorescein-biotin-dextran, 10 KDa",Thermo Fisher Scientific

(7) EpCAM silencing suppresses aggressive phenotypes and induces partial redifferentiation in anaplastic thyroid cancer cellsPLoS OneMarch 5, 2026Teruo Nakamura, Tomohiro Shibata, Ken-Ichi Itocontaining collagenase A (10103586001; Roche Diagnostics GmbH, Mannheim, Germany) and deoxyribonuclease I (LS002138; Worthington Biochemical, Lakewood, NJ, USA) at final concentrations of 0.5% and 20 U/mL, respectively.

(8) Response of B cells specific for polyomavirus-derived oncoprotein is predictive of Merkel cell carcinoma tumor controlCancer Immunology ResearchMarch 4, 2026Haroldo J. Rodriguez Rodriguez Chevez, Allison J. Remington, Matthew D. Gray, Rian Alam, Macy W. Gilmour, Carina Morningstar, Gabriel F. Alencar, Thomas Pulliam, Erin M. McClure, Neha Singh, et al.incubation in 20 mL of digestion medium composed of RPMI plus 0.002 g DNase (Worthington Biochemical #LS002139), 0.008 g collagenase (Worthington Biochemical #NC991993), and 0.002 g hyaluronidase (Worthington Biochemical

(9) Protocol for fabrication and utilization of the device for axon-cancer cell interaction testingSTAR ProtocolsMarch 1, 2026Ines Velazquez-Quesada, Kara Allison, Vahid Alizadeh, Erkan Tüzel, Bojana GligorijevicBiologicals,Cat#S12150 "Deoxyribonuclease I (15,000 units in 6 mL HBSS)",Worthington Biochemical,Cat#LS002139 Cell strainer mesh 40 μm,Corning,Cat#431750 Glass Pasteur pipets,Fisherbrand,Cat#13-678-20C Neurobasal-A medium

(10) Satellite Glial Cells Control Sensory Neuron Excitability via the Release of Fibulin-2bioRxivFebruary 18, 2026Irshad Ansari, Pan-Yue Deng, Sarah F. Rosen, Michael B. Thomsen, Vitaly A. Klyachko, Valeria Cavalli(Worthington Biochemical; Catalog#: LS003126), 0.1mg/mL DNase I, (Worthington Biochemical; Catalog#: LS002139), and 0.3mg/mL L-Cysteine (Sigma; Catalog#: C7352) and 10% 1M Hepes in HBSS, for 20 minutes at 37 °C.

(11) Unravelling genome-wide mosaic microsatellite mutations at single-cell resolutionbioRxivFebruary 6, 2026Chunyi Wang, Wenxuan Fan, Weixiang Wang, Yonghe Xia, Jinhong Lu, Xiaoyu Ma, Jichuan Yu, Yunchao Zheng, Yan Luo, Wenlong Li, et al.HBSS + 2% FBS (Jackson, #017-000-121), then treated with 0.1 mg/mL DNase I (Worthington Biochemical, #LS002139) in DMEM/F12 media at 37°C for 5 minutes. After washing, the cells were filtered through a 40 μm mesh.

(12) Multimodal epigenetic and enhancer network remodeling shape the transcriptional landscape of human beige adipocytesCommunications BiologyJanuary 8, 2026Sarah Hazell Pickering, Natalia M. Galigniana, Mohamed Abdelhalim, Anita L. Sørensen, Julia Madsen-Østerbye, Manuela Zucknick, Philippe Collas, Nolwenn BriandCells on D15 were washed with PBS and treated 30 min with 200 U/ml DNAse I (Worthington Biochemical, LS002139) in DMEM/F12 10% FBS at 37 °C. After 4 washes with warm PBS, cells were lysed directly on the culture

(13) Single-cell transcriptomics reveals notch regulation in quiescent LEPR⁺ endometrial mesenchymal stem cellsStem Cell Res TherDecember 23, 2025Yuan Fang, Dandan Cao, Cheuk-Lun Lee, Philip C. N. Chiu, Ernest H. Y. Ng, William S. B. Yeung, Rachel W. S. ChanWorthington Biochemical Corporation, USA, #LS004182) and deoxyribonuclease type I (40 μg/ml, Worthington Biochemical Corporation, #LS002139) in a shaking water bath for 1 h at 37 °C as described [23]. After two rounds of enzymatic digestion,

(14) Protocol for culturing olfactory epithelium organoids supporting neuronal differentiationSTAR ProtocolsDecember 1, 2025Juliana Gutschow Gameiro, Jussi Virtanen, Liam Lee, James E. Schwob, Marco Aurélio Fornazieri, Brian Lin,Thermo Fisher Scientific,Cat# 14175095 Papain,Worthington Biochemical,Cat# LS003119 DNase I,Worthington Biochemical,Cat# LS002139 DMEM/F12,Thermo Fisher Scientific,Cat# 1132033 Primocin 1x,InvivoGen,Cat# ant-pm Recombinant murine

(15) Fosl1 is a transcriptional effector of BRAF V600E-driven intestinal tumorigenesisiScienceNovember 21, 2025Zakia Alam, Rebecca Nightingale, Analia Lesmana, Cheng Liu, Laura J. Jenkins, Mark F. Richardson, Lawrence Croft, Ian Y. Luk, Camilla M. Reehorst, Fiona Chionh, et al.,Thermo Fisher Scientific,Cat# 10100147 Deoxyribonuclease I (DNase I),Worthington Biochemical corporation,Cat# LS002140 Trypsin (2.5%),Thermo Fisher Scientific,Cat# 15090-046 Penicillin-Streptomycin,Thermo Fisher Scientific,Cat#

(16) Type I interferons enhance human dorsal root ganglion nociceptor excitability and induce TRPV1 sensitizationJCI InsightOctober 8, 2025Úrzula Franco-Enzástiga, Keerthana Natarajan, Felipe Espinosa, Rafael Granja-Vazquez, Hemanth Mydugolam, Theodore J. PriceLS004106) solution containing 1 mg/mL STEMxyme in HBSS, 0.1 mg/mL DNase I (Worthington Biochemical, catalog LS002139), and 10 ng/mL recombinant human β-NGF (R&D Systems, catalog 256-GF) and incubated at 37°C in a gently

(17) Multi-omic integration with human dorsal root ganglia proteomics highlights TNFα signalling as a relevant sexually dimorphic pathwayPainOctober 1, 2025Allison M. Barry, Julia R. Sondermann, Joseph B. Lesnak, Feng Xian, Úrzula Franco-Enzástiga, Jayden A. O'Brien, David Gomez-Varela, Morgan K. Schackmuth, Stephanie Shiers, Theodore J. Price, et al.Systems, Minnesota, USA, 256-GF), and 0.1 mg/mL of DNAse I (Worthington Biochemical, Lakewood, USA, LS002139) in HBSS without calcium and magnesium (Thermo Scientific, Massachusetts, USA, 14170-112). The tubes

(18) Peripheral nerve-targeting and pain-promoting transcriptomic signatures in early Guillain-Barré syndromebioRxiv : the preprint server for biologySeptember 25, 2025O'Brien JA, Lesnak JB, Sankaranarayanan I, Arendt-Tranholm A, Inturi N, Sadasivuni S, Mydugolam H, Sadler KE, Price TJ, Ubogu EE.1 mg/mL Stemxyme I (Worthington Biochemical, LS004106), 0.1 mg/mL DNAse I (Worthington Biochemical, LS002139), and 10ng/mL recombinant human β-NGF (R&D Systems, 256-GF) in HBSS without calcium and magnesium (Thermo

(19) Chronic Waterborne Exposure to Polystyrene Microplastics Induces Kupffer Cell Polarization Imbalance and Hepatic Lipid AccumulationThe FASEB JournalSeptember 15, 2025Ting Li, Zhenghong Yao, Yuxin Huang, Ran Li, Lu Zhang, Rucheng Chen, Weijia GuGibco, China), collagenase (#LS004188, Worthington Biochemical Corporation, USA), Deoxyribonuclease I (#LS002138, Worthington Biochemical Corporation, USA), Percoll (#17089109‐1, Cytiva, China), red blood cell lysis

(20) Tabula Sapiens reveals transcription factor expression, senescence effects, and sex-specific features in cell types from 28 human organs and tissuesbioRxivSeptember 13, 2025The Tabula Sapiens Consortium, Stephen R QuakeWorthington Biochemical Corporation LS004182) and DNase I (200 U/mL: Worthington Biochemical Corporation LS002139) at 37°C for 90 minutes. During digestion, the mixture was pipetted every 15 minutes with a 10 mL pipette

Be the First to Write a Review!

Deoxyribonuclease I from Worthington Biochemical Corporation

Description

Worthington Biochemical Corporation

Citations (85)

Reviews

Deoxyribonuclease I from Worthington Biochemical Corporation

About Biocompare

Advertise with Us

Specialized Search Tools

Site Map