Deoxyribonuclease I LS002006 from Worthington Biochemical Corporation

Product Specs
ItemDeoxyribonuclease I
CompanyWorthington Biochemical Corporation
Price $96.00Supplier Page View Company Product Page
Catalog NumberLS002006
Source/Expression SystemBovine Pancreas
StorageStore at 2-8C. PROTECT FROM MOISTURE
Activity≥2,000 Kunitz units per mg dry weight
Size20 mg

Add to Compare List

Worthington Biochemical Corporation

Lakewood, New Jersey 8701

United States

Phone: 1.800.445.9603
1.732.942.1660

Email: custservice@worthington-biochem.com

Company Profile

Website: worthington-biochem.com

(1) Microbiota-derived secondary bile acids promote STING activation and antitumor activitybioRxivApril 12, 2026Xinglin Yang, Xing Zhang, Weichao Li, Anant Gharpure, Althea Hansel-Harris, Andreas F. Tillack, Chongyang Wu, Yan-Zhu Hsieh, Ariana Sulpizio, Kyong T. Fam, et al.RPMI containing 1.5 U/mL Liberase TM (Roche, 5401119001), 0.2 mg/mL DNase I (Worthington Biochemical, LS002006), and ceramic spheres (6.35 mm, MP Biomedicals, 116540424-CF). The tissue was incubated at 37 °C with

(2) A Cisplatin-Based Prodrug Inhibits Nucleotide Excision Repair Independently of Chromatin Accessibility to Overcome ResistanceBiomoleculesApril 7, 2026Ya’ara Negev-Korem, Hadar Golan-Berman, Elisheva Heilbrun, Subhendu Karmakar, Yoram Soroka, Marina Frušić-Zlotkin, Ofer Chen, Hiba Hassanain, Esther Stern, Ori Wald, et al.Prior to beginning the ATAC-seq protocol, drug-containing media was replaced with 200 units/mL DNase (LS002006, Worthington Biochemical Corp, Lakewood, NJ, USA) in 1.2 mM MgCl2 and 0.5 mM CaCl2 for 30 min. ATAC-seq

(3) Myofibroblast programming blocks differentiation of TLS-organizing fibroblastic reticular cells in pancreatic cancerCancer CellMarch 26, 2026Elijah Kirschstein, Olivia Harder, Jordan Krull, Madison Sikorski, Shrijan Khanal, Morgan Mack, Carl F. Ware, Elizabeth Evans, Michael J. Gough, Qin Ma, et al.#328420250 "Collagenase, Type IV",Worthington Biochemical,Cat#LS004186 DNase I,Worthington Biochemical,Cat #LS002004 Bovine serum albumin (BSA),Sigma-Aldrich,Cat #A9418 EDTA,Thermo Fisher Scientific,Cat #AM9261 Trypsin-EDTA

(4) Epigenetic memory of colitis promotes tumour growthNatureMarch 25, 2026Surya Nagaraja, Lety Ojeda-Miron, Ruochi Zhang, Ena Oreskovic, Conrad Hock, Yan Hu, Daniel Zeve, Karina Sharma, Roni R. Hyman, Qiming Zhang, et al.(Millipore, C9263-25MG), 1.25 U ml−1 dispase (Millipore, D4693-1G), 1 U ml−1 DNase (Worthington Biochemical, LS002004) and 5 μM Y-27632 (R&D, 1254). Cells were washed with 0.1% BSA/PBS, stained with Calcein Red-AM (BioLegend,

(5) Pain Outcome Determines the Sensitivity to Peripheral Opioid Antagonism of Morphine, Ibuprofen, and Their Combination in Laparotomized MicePharmaceuticsMarch 21, 2026Makeya A. Hasoun, Miriam Santos-Caballero, Miguel Á. Huerta, María Robles-Funes, Amada Puerto-Moya, M. Carmen Ruiz-Cantero, Enrique J. Cobos, Rafael González-Canosolution containing 1 mg/mL collagenase IV (LS004188, Worthington, Lakewood, NJ, USA) and 0.1% DNase I (LS002007, Worthington Biochemical Corporation, Lakewood, NJ, USA). This digestion proceeded under continuous

(6) Human neuromodulatory assembloids to study serotonin signaling and diseasebioRxivMarch 13, 2026Sabina Kanton, Xiangling Meng, Chunyang Dong, Fikri Birey, Dong Wang, Noah Reis, Se-Jin Yoon, Ji-Il Kim, James P. McQueen, Noriaki Sakai, et al.ethylenediaminetetraacetic acid (EDTA), 26 mM NaHCO3, 125 U ml−1 Deoxyribonuclease I (Worthington Biochemical, LS002007) and 6.1 mM L-cysteine (Sigma-Aldrich, C7880)) for 45 mins at 37°C with swirling in between. Then, organoids

(7) Microbiome-produced nicotinic acid controls colon regional identity and injury susceptibilityCellMarch 10, 2026Jérémie Rispal, Jasmine R. Garcia, Brisa Palikuqi, Manasa Vegesna, Dedeepya Vaka, Seung Woo Kang, Coralie Trentesaux, Juan Du, Nicola R. Realini, Paige N. Spencer, et al.acid,Invitrogen,Cat# 15575020 Dispase II,Millipore Sigma,Cat# D4693 DNase I,Worthington Biochemical,Cat# LS002007 Tamoxifen,Millipore Sigma,Cat# T5648-5G Corn Oil,Millipore Sigma,Cat# C8267 Paraformaldehyde,Fischer

(8) Co-Delivery of Synaptogenic and Angiogenic Nanoparticles in MAP Scaffolds Enhances Post-Stroke Synapse FormationJournal of Materials Chemistry BFebruary 25, 2026Nhi Van Phan, Jeremy Lee Thomas, Aiden Pasinsky, Zoe Meadows, Ting Ting Li, Augustus Adams, Yike Zhu, Anna Edgcomb, Yi Shi, Sihan Lyu, et al.Trypsin/EDTA (Gibco, Cat. No. 25200056) with 500 µL of 40 000 U mL−1 DNase (Worthington Biochemical, Cat. No. LS002006) that had been equilibrated in a CO2 incubator for a minimum of 30 minutes beforehand. Cortices were

(9) Use of a human immortalized microglia cell line to study recognition, phagocytosis, and intracellular survival of Cryptococcus neoformansmSphereFebruary 24, 2026Robbi L. Ross, Kassandra Arias-Parbul, Zane M. Douglass, Katrina L. Adams, Felipe H. Santiago-Tirado[Worthington Biochemical LS003126] dissolved in EBSS [Invitrogen], 1× DNase I [Worthington Biochemical LS002007; 500× stock solution prepared by dissolving 12,500 U of DNase I in 1 mL of EBSS]) was added to the brain

(10) Peptide‐Induced Ferroelectricity in Charge‐Transfer Supramolecular MaterialsAdvanced MaterialsFebruary 1, 2026James V. Passarelli, Yang Yang, Cara S. Smith, Jing Hao, Dhwanit R. Dave, Ashwin Narayanan, Zaida Álvarez, Broderick K. Johnson, Kelly A. Marshall, Ivan Fithian, et al.(Gibco, Cat. No. 25200072) solution with 250 µL of 4000 U/mL DNAse I (Worthington Biochemical, Cat. No. LS002006). After 10 min, cortices were placed and then mechanically dissociated in 5 mL of pre‐plating media

(11) Interpretable inflammation landscape of circulating immune cellsNature MedicineFebruary 1, 2026Laura Jiménez-Gracia, Davide Maspero, Sergio Aguilar-Fernández, Francesco Craighero, Maria Boulougouri, Max Ruiz, Domenica Marchese, Ginevra Caratù, Jose Liñares-Blanco, Miren Berasategi, et al.incubated during 10 minutes at room temperature with 0.1 mg ml−1 DNAse I (Worthington Biochemical, PN LS002007) to eliminate ambient DNA and favor the resuspension of the pellet. Cells were filtered with a 40-µm

(12) Epigenomic, transcriptomic, and proteomic characterization of breast cancer cell line reference samplesCell Reports MethodsJanuary 26, 2026Chirag Nepal, Wanqiu Chen, Zhong Chen, John A. Wrobel, Ling Xie, Wenjing Liao, Chunlin Xiao, Adrew Farmer, Malcolm Moos, Wendell Jones, et al.peptides, and recombinant proteins" ,, Deoxyribonuclease I (DNase I),Worthington Biochemical Corporation,LS002007 MgCl2 solution,Sigma-Aldrich,68475 NaCl solution,Sigma-Aldrich,S5150 Nonidet P40 Substitute,Sigma-Aldrich,11332473001 Digitonin

(13) Erythrocyte-microglia crosstalk contributing to sex differences in pediatric brain tumorigenesisResearch SquareJanuary 20, 2026Baoli Hu(Worthington Biochemical Corporation, LS004209), 1 mg/ml Deoxyribonuclease I (Worthington Biochemical Corporation, LS002007) and 2 mg/ml soybean trypsin inhibitor (Worthington Biochemical Corporation, LS003587) in DPBS for 10

(14) A Human Model of Oligodendrocyte Development Shows MCL-1 Influences Oligodendrocyte MorphogenesisGliaDecember 19, 2025Melanie Gil, Marina R. Hanna, Vivian Gamaand cells were resuspended in DMEM/F12 supplemented with 100 μg/mL DNase (Worthington Biochemical, LS002006). After incubating in DNase, cell suspension was further dissociated by gently pipetting 7–10 times.

(15) Culturing hypoxia-primed mesenchymal stem cells in xeno- and serum-free conditions facilitates the synthesis of an extracellular matrix-based biologic with augmented therapeutic potential for the treatment of diabetic woundsStem Cell Research & TherapyDecember 2, 2025Kwok Keung Lit, Cheuk Kwan Owen Li, Zhamilya Zhirenova, Anna BlockiResidual DNA was removed by subsequent incubation at 37◦C for 15 min with 0.04 mg/ml DNAse I (Cat. No.: LS002007, Worthington Biochemical, Lakewood, United States) in 1x Dulbecco′s Phosphate Buffered Saline with calcium

(16) Protocol for transcriptomic and epigenomic analysis of JAK inhibitor sensitivity in IFN-γ-primed human macrophages using ATAC-seq and RNA-seqSTAR ProtocolsDecember 1, 2025Geunho Kwon, Junho Noh, Jaehyun Lee, Keunsoo Kang, Kyuho Kanginterferon-γ, human (hIFN-γ)",Roche,Cat# 11040596001 Deoxyribonuclease I,Worthington Biochemical,Cat# LS002004 Dulbecco’s phosphate-buffered saline,BIOWEST,Cat# L0615-500 "Trypan blue solution, 0.4%",Gibco,Cat#

(17) TAF1 is required for fetal but not adult hematopoiesis in miceDevelopmental CellNovember 3, 2025Fan Liu, Jingyin Yue, Francesco Tamiro, Jun Sun, Pradeep Kumar Reddy Cingaram, Krystal Lisa Hossack, Concepcion Martinez Caja, Ye Xu, Chuan Chen, Felipe Beckedorff, et al.3 mice in control group and 2 mice in cKO group, and treated with DNase I (Worthington Biochemical, LS002007) in PBS for 30 min at 37°C to remove the dead cells and DNA debris. Cells were then lysed with RSB buffer

(18) Microglia-astrocyte crosstalk regulates synapse remodeling via Wnt signalingCellSeptember 18, 2025Travis E. Faust, Yi-Han Lee, Ciara D. O’Connor, Margaret A. Boyle, Georgia Gunner, Violeta Durán-Laforet, Loris L. Ferrari, Robert E. Murphy, Ana Badimon, Kristina Sakers, et al.added to 1 vial of Papain (LK003178 Worthington Biochemical; Lakewood, NJ) supplemented with DNAse (LS002007 Worthington Biochemical) for 45 minutes at 32°C. Cortical pieces were then triturated in sequential

(19) Protocol for establishing genetically engineered murine lung organoids mimicking cell plasticity and regenerationSTAR ProtocolsSeptember 1, 2025Bongjun Kim, Jae-Il ParkLS004197 Elastase,Worthington Biochemical,Cat# ESL LS002294 DNase I,Worthington Biochemical,Cat# D LS002007 Bovine gelatin,Sigma,Cat# G1393 EDTA solution,Sigma,Cat# E7889 Heparin,Sigma,Cat# H3149 Endothelial

(20) Syndecan-4 interacts directly with β-parvin and regulates the ILK-PINCH-β-parvin complex, the β-parvin-β-PIX-Rac1 axis, and cardiomyocyte geometry in a sex-dependent mannerFrontiers in Cell and Developmental BiologyAugust 29, 2025Sabrina Bech Mathiesen, Thea Parsberg Støle, Andreas Romaine, Marianne Lunde, Marita Martinsen, Jan Magnus Aronsen, Ivar Sjaastad, William E. Louch, Geir Christensen, Cathrine Rein Carlsonbuffer containing 1 mg/mL BSA. Chunks were then transferred to a falcon tube containing 0.2 mg DNase (LS002006, Worthington Biochemical Corporation), collagenase, and 250 µL BSA. Isolated cells were then filtered

Be the First to Write a Review!

Deoxyribonuclease I from Worthington Biochemical Corporation

Description

Worthington Biochemical Corporation

Citations (65)

Reviews

Deoxyribonuclease I from Worthington Biochemical Corporation

About Biocompare

Advertise with Us

Specialized Search Tools

Site Map