UNC5B Protein, Rat, Recombinant (hFc Tag) PR53865M4 from Leading Biology

Description

The netrin-1 receptor, UNC-5 Homology B, or UNC5B plays vital roles in angiogenesis, inflammation, embryonic development and carcinogenesis. Overexpression of UNC5B human colon epithelial cells suppressed dextran sodium sulfate, or DSS-induced apoptosis and caspase-3 activity. Besides, is a potential anti-neoplastic target in bladder cancer progression and inflammatory arthritis

Product Specs
ItemUNC5B Protein, Rat, Recombinant (hFc Tag)
CompanyLeading Biology
Price $667.00Get Pricing Get Quote for this Product
Catalog NumberPR53865M4
TypeRecombinant Protein
FormatLyophilized
Size100 ug
Source/Expression SystemHEK293 Cells
Molecule NameUNC5B
Molecular WeightThe recombinant rat UNC5B/Fc is a disulfide-linked homodimer. The reduced monomer comprises 588 amino acids and has a predicted molecular mass of 65.7 kDa. The apparent molecular mass of the protein is approximately 72-90 kDa in SDS-PAGE under reducing conditions due to glycosylation
Conjugate/TagC-hFc
ActivityAt Leading Biology, the biological activity of a recombinant protein is routinely measured using a bioassay, e.g. chemotaxis or cell proliferation assay, enzyme assay, or a functional ELISA. When a recombinant protein is an enzyme, specific activity is derived from an enzymatic assay. Each enzyme is tested for potency by cleavage of a substrate. We are in the process of updating the biological activity data. If you have any questions regarding this update, please feel free to contact our technical support team
Purity> 85 % as determined by SDS-PAGE
SpeciesRat
NCBI Full Gene Nameunc-5 netrin receptor B
NCBI Gene AliasesUnc5h2