IL-23 Protein, Human, Recombinant (His Tag) PH50210M2 from Leading Biology

Product Specs
ItemIL-23 Protein, Human, Recombinant (His Tag)
CompanyLeading Biology
Price $1,950.00Get Pricing Get Quote for this Product
Catalog NumberPH50210M2
NCBI Gene AliasesIL-23A, CLMF, IL-23, IL23P19, NKSF, NKSF2, CLMF2, P19, SGRF, IMD29, IMD28, IL-12B
NCBI Full Gene Nameinterleukin 12B, interleukin 23 subunit alpha
SpeciesHuman
Purity> 90 % as determined by SDS-PAGE
Activity1. Measured by its ability to bind biotinylated recombinant human IL12RB1 in a functional ELISA. 2. Measured by its binding ability in a functional ELISA. Immobilized human IL23A-His+IL12B-His at 10 µg/ml (100 µl/well) can bind human IL23R-Fc (Cat:PH51521M4). The ECof human IL23R-Fc (Cat:PH51521M4) is 0.28-0.66 µg/ml. 3.Measured by its binding ability in a functional ELISA. Immobilized human IL23A-His+IL12B-His at 10 µg/ml (100 µl/well) can bind Cynomolgus IL23R-Fc (Cat:PK53943M4). The ECof Cynomolgus IL23R-Fc (Cat:PK53943M4) is 0.14-0.35 µg/ml. 4. Measured by its ability to induce IL17 secretion by mouse splenocytes. The EDfor this effect is 4-20 ng/mL
Conjugate/TagC-His
Molecular WeightThe recombinant IL23 heterodimer of human IL23A/IL12B comprises 498 (181+317) amino acids and has a calculated molecular mass of 56.3 (20.1+36.2) kDa. The apparent molecular mass of rhIL23 heterodimer is approximately 22.6 & 42.8 kDa respectively in SDS-PAGE under reducing conditions
Molecule NameIL12B & IL23A
Source/Expression SystemHEK293 Cells
Size1 mg
FormatLyophilized
TypeRecombinant Protein