GITRL Protein, Human, Recombinant (ECD, mFc Tag) PH52279M4 from Leading Biology

Description

The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptor TNFRSF18/AITR/GITR. It has been shown to modulate T lymphocyte survival in peripheral tissues. This cytokine is also found to be expressed in endothelial cells, and is thought to be important for interaction between T lymphocytes and endothelial cells

Product Specs
ItemGITRL Protein, Human, Recombinant (ECD, mFc Tag)
CompanyLeading Biology
Price $1,950.00Get Pricing Get Quote for this Product
Catalog NumberPH52279M4
TypeRecombinant Protein
FormatLyophilized
Size1 mg
Source/Expression SystemHEK293 Cells
Molecule NameTNFSF18
Molecular WeightThe recombinant human TNFSF18 consists of 361 amino acids and predicts a molecular mass of 40.9 kDa. It migrates as an approximately 45.5 kDa band in SDS-PAGE under reducing conditions
Conjugate/TagC-mFc
ActivityAt Leading Biology, the biological activity of a recombinant protein is routinely measured using a bioassay, e.g. chemotaxis or cell proliferation assay, enzyme assay, or a functional ELISA. When a recombinant protein is an enzyme, specific activity is derived from an enzymatic assay. Each enzyme is tested for potency by cleavage of a substrate. We are in the process of updating the biological activity data. If you have any questions regarding this update, please feel free to contact our technical support team
Purity> 90 % as determined by SDS-PAGE
SpeciesHuman
NCBI Full Gene NameTNF superfamily member 18
NCBI Gene AliasesAITRL, GITRL, TL6, TNLG2A, hGITRL
Research AreaCancer Drug Targets