SDS-PAGE of human alpha synuclein S87N monomer under reducing conditions showing the protein purity. Lane 1: Biorad All Blue Standards (3uL), Lane 2: human alpha synuclein S87N monomer (2ug), lane 3: human alpha synuclein S87N monomer (4ug).
Fibril formation and seeding activity of human alpha synuclein S87N mutant measured by ThT in vitro. Human S87N mutant monomers self-aggregate faster than human wild-type monomers. Human S87N mutant pre-formed fibrils rapidly seed S87N mutant monomers and mouse wild-type monomers. Human S87N mutant fibrils also seed human wild-type monomers, although less aggressively than mouse wild-type monomers.
Supplier Page from StressMarq Biosciences Inc for Alpha Synuclein S87N Mutant Monomers