Human TIGIT / VSTM3 Protein (His Tag) 10917-H08H3 from Sino Biological, Inc.

Product Specs
ItemHuman TIGIT / VSTM3 Protein (His Tag)
CompanySino Biological, Inc.
Price $1,156.00Supplier Page View Company Product Page
Catalog Number10917-H08H3
TypeRecombinant protein
Molecule NameTIGIT
SpeciesHuman
NCBI Full Gene NameT cell immunoreceptor with Ig and ITIM domains
NCBI Gene AliasesVSIG9, VSTM3, WUCAM
Conjugate/TagC-His
FormatLyophilized from sterile PBS, pH 7.4
Source/Expression SystemHEK293 Cells
Molecular WeightThe recombinant human TIGIT predicts a molecular mass of 28.81 kDa. It migrates as an approximately 36.72 kDa band in SDS-PAGE under reducing conditions
Activity1.Immobilized Recombinant Human CD155 / PVR / NECL5 Protein (Fc Tag) (Cat:10109-H02H) at 2µg/mL (100µL/well) can bind Recombinant Human TIGIT / VSTM3 Protein (His Tag) (Cat:10917-H08H3), the EC50 is 6-18 ng/mL(QC tested). 2.Immobilized Anti-Tigit (Research Grade Clone Tiragolumab) at 2 µg/mL (100 µL/well) can bind Recombinant Human TIGIT / VSTM3 Protein (His Tag) (Cat: 10917-H08H3), the EC50 is 1.2-4 ng/mL (Routinely tested). 3.Loaded Recombinant Human CD155/PVR Protein, hFc Tag (Cat. No. 10109-H02H) on ProA Biosensor, can bind Recombinant Human TIGIT Protein, His Tag (Cat. No. 10917-H08H3) with an affinity constant of 0.51 nM as determined in BLI assay (Sartorius Octet RED384) (Routinely tested). 4.Recombinant Human CD155/PVR Protein, hFc Tag (Cat. No. 10109-H02H) captured on Protein A chip can bind Recombinant Human TIGIT Protein(Dimer), His Tag (Cat. No. 10917-H08H3) with an affinity constant of 3.28 nM as determined in an SPR assay (Biacore 8K) (Routinely tested). 5.Anti-Tigit (Research Grade Clone MITG7192A) captured on Protein A chip, can bind Recombinant Human TIGIT / VSTM3 Protein (His Tag) (Cat: 10917-H08H3) with an affinity constant of 48.600 pM as determined in an SPR assay (Biacore 8K) (Routinely tested). 6.Immobilized Recombinant Human TIGIT / VSTM3 Protein (His Tag) (Cat: 10917-H08H3) at 1 µg/mL (100 µL/well) can bind Recombinant Human Nectin 3 Protein (Fc Tag) (Cat: 10852-H02H), the EC50 is 2.4 µg/mL (Routinely tested)
Purity≥ 95 % as determined by SDS-PAGE. ≥ 95 % as determined by SEC-HPLC. ≥ 95 % as determined by SEC-MALS(Routinely tested)
Size500 µg