Description
Human IL-7 R alpha/CD127 Recombinant Protein Mouse IgG Fc Tag Lyophilized has been recombinantly produced in HEK293 cells.
Interleukin-7 receptor subunit alpha (IL7Ra) is also known as CD antigen CD127, which belongs to the type I cytokine receptor family and type 4 subfamily. IL7Ra/CD127 contains 1 fibronectin type-III domain. IL7Ra/CD127 is expressed on various cell types, including naive and memory T cells and many others. IL7Ra/CD127 is receptor for interleukin-7 and also acts as a receptor for thymic stromal lymphopoietin (TSLP). The IL7 receptor is a heterodimer of IL7R and IL2RG. The TSLP receptor is a heterodimer of CRLF2 and IL7R.
This protein carries a mouse IgG2a Fc Tag at the C-terminal. The protein has a calculated MW of 52.0 kDa. The protein migrates as 65-115 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation