Description
Human Factor VII Purified has been purified from human plasma. This is a frozen liquid buffered in 20 mM Tris-HCl/0.1 M NaCl/1mM Benzamidine/pH 7.4, with a concentration of 2mg/ml and a purity of greater than 95% as determined by SDS-PAGE analysis (no reduction when incubated with 2-mercaptoethanol).
Factor VII works in conjunction with Tissue Factor (Factor III) to begin the process of coagulation in the body. When blood vessels are injured, Tissue Factor enters the bloodstream (normally it is isolated to the outside of blood vessels) and binds to Factor VII. Factor VII is vitamin K dependent and produced in the liver