Description
Recombinant EBV glycoprotein H and L expressed and purified from 293 cells
Herpesviruses have an envelope and an outer lipid bilayer which contains twelve surface glycoproteins. For infectivity to be attained, the double stranded DNA genome of EBV must enter the host cell through means of fusion of its envelope with the cellular membrane or via endocytosis.
Epstein–Barr virus (EBV) can infect both B cells and epithelial cells. The mechanisms for entering these two cells are different. The viral three-part glycoprotein complexes of gHgL/gp42 mediate B cell membrane fusion