Description
TSSK2 (Testis Specific Serine Kinase 2) is a testis-specific serine/threonine-protein kinase that is required during spermatid development and phosphorylates TSKS at 'Ser-288’ and SPAG16. TSSK2 is involved in the late stages of spermatogenesis during the reconstruction of the cytoplasm. During spermatogenesis, TSSK2 is required for the transformation of a ring-shaped structure around the base of the flagellum originating from the chromatoid body. Diseases associated with TSSK2 include Hyperprolinemia, Type I and Combined D-2- And L-2-Hydroxyglutaric Aciduria