Description
TNF-alpha Recombinant Protein His Tag Lyophilized has been recombinantly produced in HEK293 cells.
Tumor necrosis factor alpha (TNFalpha) is a cytokine produced primarily by monocytes and macrophages. It is found in synovial cells and macrophages in the tissues.The primary role of TNFalpha is in the regulation of immune cells. TNFalpha is able to induce apoptotic cell death, to induce inflammation, and to inhibit tumorigenesis and viral replication. Dysregulation of TNFalpha production has been implicated in a variety of human diseases, including major depression, Alzheimer's disease and cancer. Recombinant TNFalpha is used as an immunostimulant under the INN tasonermin. TNFalpha can be produced ectopically in the setting of malignancy and parallels parathyroid hormone both in causing secondary hypercalcemia and in the cancers with which excessive production is associated.
This recombinant protein can be used for E, WB