Description
Human Activin B Recombinant Protein Lyophilized has been recombinantly produced in High-5 Insect cells.
Activin B is a TGF-beta family member that exhibits a wide range of biological activities, including regulation of embryogenesis, osteogenesis, hematopoiesis, reproductive physiology and hormone secretion from the hypothalamic, pituitary and gonadal glands. Activin B, like certain other members of the TGF-beta family, signals through the ActRII receptor (Activin Receptor type II). Activins are homodimers or heterodimers of different alpha subunits. They are produced as precursor proteins with an amino terminal propeptide that is cleaved to release the C-terminal bioactive ligand. Human Activin B is a 25.6 kDa disulfide-linked homodimer consisting of two betaB chains, each containing 115 amino acid residues