Description
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation
deacetylation alters chromosome structure and affects transcription factor access to DNA. This protein belongs to class II of the histone deacetylase
acuc
apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3