Description
Human TNF beta Recombinant Protein Tag Free Lyophilized has been recombinantly produced in E Coli.
Tumor Necrosis Factor beta (TNF-kappaBeta) is a secreted protein belonging to the tumor necrosis factor family. TNF-kappaBeta binds to TNFRSF1A/TNFR1, TNFRSF1B/TNFBR and TNFRSF14/HVEM in homotrimeric form, binds to TNFRSF3/LTBR in heterotrimeric form with LTB. TNF-kappaBeta forms heterotrimers with lymphotoxin-beta, which anchors TNF-kappaBeta to the cell surface. TNF-kappaBeta mediates the inflammatory, immunostimulatory, and antiviral response, involves in the formation of second lymphoid organs during development, has a role in apoptosis. TNF-kappaBeta is produced by lymphocytes and cytotoxic for a variety of tumor cells in vitro and in vivo.
This recombinant protein can be used for biological assays