Description
Human, Mouse IL-1alpha Recombinant Protein (Animal Free) Lyophilized has been recombinantly produced in E Coli.
IL-1alpha is a non-secreted, proinflammatory cytokine produced in a variety of cells, including monocytes, tissue macrophages, keratinocytes, and other epithelial cells. Both IL-1alpha and IL-1beta bind to the same receptor and have similar, if not identical, biological properties. These cytokines have a broad range of activities including the stimulation of thymocyte proliferation by inducing IL-2 release, Bcell maturation and proliferation, mitogenic FGF-like activity and the release of prosTaglandin and collagenase from synovial cells. However, whereas IL-1beta is a secreted cytokine, IL-1alpha is predominantly a cell-associated cytokine. Recombinant Human IL-1alpha is an 18.0 kDa protein containing 159 amino acid residues