Description
ALDOC, also as known as fructose bisphosphate C, is a member of the class 1 fructose-biphosphate aldolase family. This protein is a ubiquitous enzyme that catalyzes the reversible aldol cleavage of fructose-bisphosphate and fructose 1-phospate to digydroxyacetone phosphate and either glyceral-dehyde-3-phosphate or glyceraldegyde, respectively. It is expressed specifically in the hippocampus and Purkinje cells of the brain. Recombinant human ALDOC was expressed in E Coli and purified by using conventional chromatography techniques