Description
Human IFN beta Recombinant Protein Lyophilized has been recombinantly produced in CHO cells.
Proteins of this family play an important role in inducing non-specific resistance against a broad range of viral infections. They also affect cell proliferation and modulate immune responses. Produced by peripheral blood leukocytes and lymphoblastoid cells, IFNalpha is an acid stable molecule that signals through IFNalpha/betaR, which is also used by IFNbeta. Both IFNs have similar anti-viral activity and regulate expression of MHC class I antigens. IFNalpha contains four highly conserved cysteine residues which form two disulfide bonds, one of which is necessary for biological activity. Recombinant human IFNbeta is an 20.0 kDa protein containing 166 amino acid residues. Due to glycosylation, IFNbeta has an approximate MW of 22.3 kDa based on SDS-PAGE gel and Mass Spectrometry