Description
Human TRAIL Recombinant Protein Tag Free Lyophilized has been recombinantly produced in E Coli.
Human TNFSF10 is a type II transmembrane protein with an intracellular N-terminal and a 'TNF homology domain' (THD) at the extracellular C terminal. TNFSF10 can interact with several distinct receptors. Two of these receptors that belongs to TNFR superfamily, DR4 (TRAIL-R1) and DR5 (TRAIL-R2/TRICK2), are plasma membrane proteins containing intracellular death domains essential for activating apoptosis. TNFSF10 is promising for cancer therapy because it is cytotoxic and activates apoptosis in the majority of malignant cells, but not in normal cells.
This recombinant protein can be used for biological assays