Description
The importin-alpha
beta complex and the GTPase Ran mediate nuclear import of proteins with a classical nuclear localization signal. This protein is a member of a class of approximately 20 potential Ran targets that share a sequence motif related to the Ran-binding site of importin-beta. This protein binds to the nuclear pore complex and, along with RanGTP and RANBP1, inhibits the GAP stimulation of the Ran GTPase