Description
Glycine N-methyltransferase (GNMT) catalyzes the transfer of a methyl group from S-adenosylmethionine (SAM) to glycine to yield S-adenosylhomocysteine (SAH) and N-methylglycine (sarcosine). The enzyme appears to play a significant role in maintaining the physiologically appropriate SAM-to-SAH ratio, which is thought to be a critical component of the regulation of the methylation potential of the cell