Exendin-3 (9-39) amide (trifluoroacetate salt) from Cayman Chemical

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Exendin-3 (9-39) amide (trifluoroacetate salt)

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Description

A potent antagonist of GLP-1R (Kd = 1.7 nM); inhibits exendin-3-induced increases in cAMP levels (IC50 = 20 nM); reverses GLP-1 inhibition of feeding behavior in rats when administered at 10 and 100 µg, i.c.v. into the hypothalamus