Description
Product Characteristics: Recombinant Metastasis Associated In Colon Cancer 1 (MACC1), Prokaryotic expression, Gln522-Met784 (Accession # Q6ZN28), N-terminal His and GST Tag
antibodies-online can provide customization with regards to expression system, tag location and sequence for our made to order proteins designed and produced in Germany. Please contact our customer support for further information.:
Target Information: MACC1 is a key regulator of the hepatocyte growth factor (HGF\, MIM 142409)-HGF receptor (HGFR, or MET\, MIM 164860) pathway, which is involved in cellular growth, epithelial-mesenchymal transition, angiogenesis, cell motility, invasiveness, and metastasis. Expression of MACC1 in colon cancer (MIM 114500) specimens is an independent prognostic indicator for metastasis formation and metastasis-free survival (Stein et al., 2009 [PubMed 19098908]).[supplied by OMIM, Mar 2009]