Description
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Target Information: This gene encodes a transcription factor containing an ETS DNA-binding domain. The gene can undergo a t(11\,22)(q24\,q12) translocation with the Ewing sarcoma gene on chromosome 22, which results in a fusion gene that is present in the majority of Ewing sarcoma cases. An acute lymphoblastic leukemia-associated t(4\,11)(q21\,q23) translocation involving this gene has also been identified. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]