MCP-3/CCL7 Protein, Human HY-P7242 from MedChemExpress | Biocompare.com

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MCP-3/CCL7 Protein, Human

Description

MCP-3/CCL7 Protein, Human is a CC chemokine and elicitor that binds to CCR1, CCR2 and CCR3 to mediate antiviral, antibacterial, antitumor and other immune responses. MCP-3/CCL7 Protein, Human is a recombinant human MCP-3/CCL7 protein expressed by E.coilMCP-3/CCL7 (Q24-L99)

Product Specs
ItemMCP-3/CCL7 Protein, Human
CompanyMedChemExpress
Price $75.00Supplier Page View Company Product Page
Catalog NumberHY-P7242
TypeProtein
ApplicationsBioactivity, Structure and function analysis, ELISA, SDS-PAGE, Western blotting
Size2 µg
Molecular WeightApproximately 12.97 kDa
Source/Expression SystemE. coli
Activity1. Full biological activity determined by a chemotaxis bioassay using human monocytes is in a concentration range of 10-100 ng/ml. 2. Measured by its ability to chemoattract THP-1 human acute monocytic leukemia cells. The ED₅₀ this effect is 0.08829 µg/mL, corresponding to a specific activity is 1.132×10⁴ U/mg
SpeciesHuman
NCBI Full Gene NameC-C motif chemokine ligand 7
NCBI Gene AliasesMCP3, NC28, MARC, FIC, MCP-3, SCYA7, SCYA6

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(1) Tumor-stromal crosstalk in invasion of oral squamous cell carcinoma: a pivotal role of CCL7International journal of cancerJuly 15, 2010Jung DW, Che ZM, Kim J, Kim K, Kim KY, Williams D, Kim J.

(2) Reduced tumorigenicity and augmented leukocyte infiltration after monocyte chemotactic protein-3 (MCP-3) gene transfer: perivascular accumulation of dendritic cells in peritumoral tissue and neutrophil recruitment within the tumorJournal of immunology (Baltimore, Md. : 1950)July 1, 1998Fioretti F, Fradelizi D, Stoppacciaro A, Ramponi S, Ruco L, Minty A, Sozzani S, Garlanda C, Vecchi A, Mantovani A.

(3) The human MCP-3 gene (SCYA7): cloning, sequence analysis, and assignment to the C-C chemokine gene cluster on chromosome 17q11.2-q12GenomicsMay 15, 1994Opdenakker G, Fiten P, Nys G, Froyen G, Van Roy N, Speleman F, Laureys G, Van Damme J.

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