Human IFN gamma Protein 11725-HNAE from Sino Biological, Inc.

Product Specs
ItemHuman IFN gamma Protein
CompanySino Biological, Inc.
Price $68.00Supplier Page View Company Product Page
Catalog Number11725-HNAE
TypeRecombinant protein
Molecule NameIFNG
SpeciesHuman
NCBI Full Gene Nameinterferon gamma
NCBI Gene AliasesIFG, IFI, IMD69
Conjugate/TagUnconjugated
FormatLyophilized from sterile 50mM Tris, pH 8.0
Source/Expression SystemE. coli
Molecular WeightThe recombinant human IFNG consists of 144 amino acids and predicts a molecular mass of 16.91 kDa. The molecular weight of this protein is around 35.4 kDa verified by SEC-MALS (Routinely tested)
Purity≥ 95 % as determined by SDS-PAGE. ≥ 95 % as determined by SEC-HPLC. ≥ 95 % as determined by SEC-MALS(Routinely tested)
ActivityMeasured in anti-viral assays using WISH cells infected with vesicular stomatitisvirus (VSV). The ED50 for this effect is 8-80 pg/mL
Size20 µg

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Sino Biological, Inc.

37 Industrial Blvd

Suite B

Paoli, PA 19301

United States

Phone: 215-583-7898
Fax: 267-657-0217

Email: marketing@sinobiological.com

Company Profile

Website: sinobiological.com

(1) Programmed death-ligand 1 (PD-L1) Modulates Chemokine Production Via the TLR4/TRAF6 Signaling Axis During LPS + IFN-γ-Induced Endotoxemia-mimicked SepsisInflammationJanuary 10, 2026Mu Yuan, Tong Jin, Luoquan Ao, Junyu Zhu, Weijun Wan, Quan Chen, Yuchuan Yuan, Qing Zhao, Xiang Xu, Lixing Tianthioglycolate were acquired from Sigma‒Aldrich Corporation (St. Louis, MO, USA). Recombinant Human IFN-γ (Cat# 11725-HNAE) was obtained from Sinobiological (Beijing, China). Recombinant mouse IFN-γ (Cat# 50709-MNAH) was obtained

(2) PD-L1 as a Potential Inducer for NF-κB Pathway Activation in M1-Type Macrophages During Sepsis: An Integrated Analysis Based on GEO Public Database and Multi-Omics DataJournal of Inflammation ResearchJanuary 9, 2026Mu Yuan, Tong Jin, Qing Zhao, Lixing Tian(Escherichia coli 0111:B4) and thioglycolate were from Sigma‒Aldrich (St. Louis, MO, USA). Recombinant Human IFN-γ (11725-HNAE) was from Sinobiological (Beijing, China). Trypsin, fetal bovine serum (FBS), RPMI 1640 medium, and

(3) PD-L1 mediates M1 polarization of macrophages via the AIM2/IL-18/STAT1 signaling axis during sepsisCell Communication and SignalingDecember 8, 2025Guomei Yang, Luoquan Ao, Qing Zhao, Chengyi Hu, Xiaofeng Wu, Mengwei Yao, Mu Yuan, Tong Jin, Weijun Wan, Quan Chen, et al.thioglycolate were purchased from Sigma-Aldrich (St. Louis, MO, USA). Recombinant Human IFN-γ (Cat# 11725-HNAE) was obtained from Sinobiological (Beijing, China). Recombinant mouse IFN-γ (Cat# 50709-MNAH) was obtained

(4) Succinate–GPR91 signaling promotes cardiomyocyte metabolic reprogramming and NAD+ production to alleviate HFpEFCardiovascular DiabetologyDecember 6, 2025Yumeng Jia, Wenhui Niu, Lu Liu, Qun Zhang, Dingwei Li, Tangyu Dai, Jie Du, Lei Wanginflammation (10 ng/mL IL-1β (SinoBiological, Cat#10139-HNAE), 100 ng/mL IFN-γ (SinoBiological, Cat#11725-HNAE)), diabetes (high glucose 11.1 mmol/L (Beyotime, Cat#ST491-100) with insulin deprivation), and hypertension

(5) Increasing S1P promotes M1 macrophage in chronic obstructive pulmonary disease and chronic obstructive pulmonary disease-obstructive sleep apnea overlap syndrome via S1PR1/HDAC1 signalingJournal of Thoracic DiseaseApril 30, 2025Ruoxuan Hei, Xiuping Wu, Tongtong Zhang, Min Zhang, Yue Huang, Zhou Zhou, Wendi Xiao, Wen Ai, Yanwei ChenLPS (Sigma, St. Louis, MO, USA; cat: L2880) and 25 ng/mL interferon-γ (IFN-γ; Sino Biological; cat: 11725-HNAE) for 72 hours. For M2 polarization, cells were treated with 50 ng/mL interleukin-4 (IL-4; Sino Biological;

(6) Cytokine Signature Unveils Subgroups of Patients With Immune-Mediated Sensory NeuronopathiesJournal of the peripheral nervous system : JPNSMarch 1, 2025Moritz CP, Tholance Y, Borowczyk C, Jospin F, Paul S, Antoine JC, Camdessanché JP.

(7) CD22 modulation alleviates amyloid β-induced neuroinflammationJournal of neuroinflammationFebruary 5, 2025Mai YD, Zhang Q, Fung CL, Leung SO, Chong CH.2.5 M/mL in 200 μL medium. On Day 1, PBMC was first stimulated with 10 ng/mL IFNγ (Sino Biological, 11725-HNAE). On Day 2, PBMC was stimulated with 100 ng/mL LPS with the presence of 1 μg/mL SM03 (SinoMab BioScience

(8) The antibody repertoire of autoimmune sensory neuronopathies targets pathways of the innate and adaptative immune system. An autoantigenomic approachJournal of Translational AutoimmunityJanuary 30, 2025Christian P. Moritz, Yannick Tholance, Nadia Boutahar, Coralie Borowczyk, Anne-Emmanuelle Berger, Stéphane Paul, Jean-Christophe Antoine, Jean-Philippe CamdessanchéIFN-γ (A), reference 11725-HNAS, from Chinese hamster ovary (CHO) stable cells; IFN-γ (B), reference 11725-HNAE, from E. coli cells, both from Sino Biological. Sera were diluted 1:300 and secondary antibody 1:2000.

(9) Metformin Inhibited GSDME to Suppress M2 Macrophage Pyroptosis and Maintain M2 Phenotype to Mitigate Cisplatin-Induced Intestinal InflammationBiomedicinesNovember 4, 2024Ke Jiang, Qi He, Chenhui Wang, Wen Yang, Changdong Zhou, Jian Li, Jiangbo Li, Yuke Cui, Jingqi Shi, Zhenqiao Wei, et al.(M0) were cultured for 48 h with fresh medium supplemented with 20 ng/mL IFN-γ (SinoBiological, Cat# 11725-HNAE, Beijing, China) and 100 ng/mL LPS (Thermo Fisher Scientific, Cat# 00-4976-93, Waltham, MA, USA) to

(10) Human papillomavirus-encoded circular RNA circE7 promotes immune evasion in head and neck squamous cell carcinomaNature communicationsOctober 4, 2024Ge J, Meng Y, Guo J, Chen P, Wang J, Shi L, Wang D, Qu H, Wu P, Fan C, et al.monitored under light microscopy. DC cells were obtained by adding 25 ng/ml IFN-γ (Sino Biological, 11725-HNAE, China) and continuing the culture for 1 day, followed by co-culture with tumor cell lysates for another

(11) Endosialin-positive CAFs promote hepatocellular carcinoma progression by suppressing CD8(+) T cell infiltrationJournal for immunotherapy of cancerSeptember 10, 2024Gan L, Lu T, Lu Y, Song H, Zhang J, Zhang K, Lu S, Wu X, Nie F, Di S, et al.confluency. Cells were then cultured in fresh serum-free medium containing 20 ng/mL IFN-γ (Sino Biological, #11725-HNAE) for 24 hours, before they were lysed in ice-cold RIPA buffer. Total protein was quantified using BCA

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Human IFN gamma Protein from Sino Biological, Inc.

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Sino Biological, Inc.

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Human IFN gamma Protein from Sino Biological, Inc.

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