Exendin-4 acetate HY-13443A from MedChemExpress | Biocompare.com

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Exendin-4 acetate

Description

Exendin-4 acetate (Exenatide acetate), a 39 amino acid peptide, is a long-acting glucagon-like peptide-1 receptor agonist with an IC₅₀ of 3.22 nM

Product Specs
ItemExendin-4 acetate
CompanyMedChemExpress
Price $79.00Supplier Page View Company Product Page
Catalog NumberHY-13443A
Size1 mg
ApplicationsBioactivity, Structure and function analysis, ELISA, SDS-PAGE, Western blotting
Purity99.91%
TypeChemical
Molecular Weight4246.62
FormulaC₁₈₆H₂₈₆N₅₀O₆₂S
Research AreaMetabolic Disease; Cardiovascular Disease; Cancer

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(1) Exenatide exerts direct protective effects on endothelial cells through the AMPK/Akt/eNOS pathway in a GLP-1 receptor-dependent mannerAmerican journal of physiology. Endocrinology and metabolismJune 1, 2016Wei R, Ma S, Wang C, Ke J, Yang J, Li W, Liu Y, Hou W, Feng X, Wang G, et al.

(2) Antidiabetic exendin-4 activates apoptotic pathway and inhibits growth of breast cancer cellsTumour biology : the journal of the International Society for Oncodevelopmental Biology and MedicineFebruary 1, 2016Fidan-Yaylalı G, Dodurga Y, Seçme M, Elmas L.

(3) Exenatide induces aortic vasodilation increasing hydrogen sulphide, carbon monoxide and nitric oxide productionCardiovascular diabetologyApril 2, 2014Sélley E, Kun S, Szijártó IA, Laczy B, Kovács T, Fülöp F, Wittmann I, Molnár GA.

(4) Biochemical and histological effects of exendin-4 (exenatide) on the rat pancreasDiabetologiaJanuary 1, 2010Nachnani JS, Bulchandani DG, Nookala A, Herndon B, Molteni A, Pandya P, Taylor R, Quinn T, Weide L, Alba LM.

(5) Exendin-4, a glucagon-like protein-1 (GLP-1) receptor agonist, reverses hepatic steatosis in ob/ob miceHepatology (Baltimore, Md.)January 1, 2006Ding X, Saxena NK, Lin S, Gupta NA, Anania FA.

(6) The importance of the nine-amino acid C-terminal sequence of exendin-4 for binding to the GLP-1 receptor and for biological activityRegulatory peptidesJuly 15, 2003Doyle ME, Theodorakis MJ, Holloway HW, Bernier M, Greig NH, Egan JM.

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